Kuvhiya Sutures
Kuvhiya Sutures kwakakosha pakuvhara maronda, kuve nekugona kushandisa simba rakakura kupfuura zvinonamira matishu uye nekumhanyisa maitiro ekuporesa echisikigo.Kune zvakawanda zvekuvhiya suture zvinhu zvakagamuchirwa nekuda kweichi chinangwa - senge mapurasitiki anoparara uye asingagadzirike, mapuroteni anotorwa nebiologically, uye simbi - asi kuita kwavo kwakaganhurirwa nekuoma kwavo.Zvakajairwa suture zvinhu zvinogona kukonzera kusagadzikana, kuzvimba uye kukanganisa kuporesa, pakati pemamwe matambudziko epashure pekuvhiya.
Mukuedza kugadzirisa dambudziko iri, vaongorori vekuMontreal vakagadzira hunyanzvi hwekuvhiya gel sheathed (TGS) sutures inofemerwa netendon yemunhu.
Aya anotevera-anotevera sutures ane inotsvedza, asi yakaoma gel envelopu, kutevedzera chimiro chezvinyoro zvinobatanidza tishu.Mukuisa iyo yakaoma gel sheathed (TGS) yekuvhiya sutures pabvunzo, vaongorori vakawana kuti iyo inenge isina friction gel yepasi yakadzikisa kukuvadzwa kunowanzo kukonzerwa nevechinyakare sutures.
Mamiriro ekuvhiya akajairika ave aripo kwemazana emakore uye anoshandiswa kubata maronda pamwe chete kusvika kupora kwapera.Asi ivo vari kure nekwakanakira kugadzirisa matishu.Iwo rough fibers anogona kucheka nekukuvadza matishu atoparara, zvichitungamira mukusagadzikana uye mushure mekuvhiyiwa matambudziko.
Sekureva kwevaongorori, chikamu chedambudziko neakajairwa sutures ndiko kusawirirana pakati pezvinyoro zvedu zvinyoro uye kuomarara kwesutures iyo inokwesha inopesana nekubata tishu.McGill University neINRS Énergie Matériaux Télécommunications Research Center timu yakatarisana nedambudziko iri nekugadzira tekinoroji nyowani inotevedzera makanika ematendon.
Kufemerwa neHuman Tendons
Kugadzirisa dambudziko iri, timu yakagadzira tekinoroji nyowani inotevedzera ma mechanics ematendon."Magadzirirwo edu anofemerwa nemuviri wemunhu, iyo endotenon sheath, iyo yakaoma uye yakasimba nekuda kweiyo mbiri-network chimiro.
Inosunga collagen fibers pamwe chete nepo elastin network ichiisimbisa, "anodaro munyori anotungamira Zhenwei Ma, mudzidzi wePhD achitungamirirwa naProfessor Jianyu Li paMcGill University.
Iyo endotenon sheath inoumba nzvimbo inotsvedza kuti ideredze kupokana nematishu akatenderedza uye zvakare inoburitsa zvinhu zvekugadzirisa matishu mukukuvara kwetendon, inosanganisira maseru netsinga dzeropa uye kutakura kwevanhu uye kugadzirisa tendon.
Tough gel sheathed (TGS) sutures yekuvhiya inogona kugadzirwa kuti ipe mishonga yemunhu zvichienderana nezvinodiwa nemurwere, vanodaro vaongorori.
Next Generation Suture Materials
Iyo McGill University sutures ine yakakurumbira yekutengesa yakarukwa suture mukati mehamvuropu yegel inotevedzera sheath iyi.Iyo yakaoma gel sheathed (TGS) sutures yekuvhiya inogona kugadzirwa kusvika 15cm kureba uye inogona kuomeswa-kuomeswa kuchengetedza kwenguva refu.
Kutanga vachishandisa ganda renguruve uyezve modhi yemakonzo, vaongorori vakaratidza kuti vanogona kushandiswa kune akajairwa kuvhiyiwa stitches uye mapfundo uye anoshanda pakuvhara maronda pasina kukonzera hutachiona.
Iyo yakaoma gel sheathed (TGS) yekuvhiya sutures - mune imwe yakafanana ne endotenon sheaths - inogona zvakare kugadzirwa kuti ipe munhu wega ronda kurapwa.
Personalized Maronda Kurapa
Vatsvakurudzi vakaratidza musimboti uyu nekurodha sutures ine antibacterial compound, pH inonzwa microparticles, zvinodhaka uye fluorescent nanoparticles yekurwisa hutachiona, kutarisa mubhedha wemaronda, kuendesa zvinodhaka uye bioimaging application.
“Tekinoroji iyi inopa chishandiso chakasiyana-siyana chepamusoro pekugadzirisa maronda.Isu tinotenda kuti inogona kushandiswa kuendesa zvinodhaka, kudzivirira kutapukira, kana kutarisisa maronda neine-infrared imaging,” anodaro Li weDhipatimendi reMechanical Engineering.
"Kugona kutarisa maronda munharaunda uye kugadzirisa nzira yekurapa kuti apore zviri nani inzira inofadza yekuongorora," anodaro Li, uyo ariwo Canada Research Chair muBiomaterials uye Musculoskeletal Health.
Mareferensi ekutanga:
1. McGill University
2. Bioinspired tough gel sheath for robust and versatile surface functionalization.Zhenwei Ma et.al.Science Advans, 2021;7 (15): eabc3012 DOI: 10.1126/sciadv.abc3012
Nguva yekutumira: Kubvumbi-02-2022